Overload Maker & Tokah - Go! lyrics

Substance abuse has been found to affect the brain
The main organ in the central nervous system
In two key ways
The first is that chronic substance abuse
Disrupts the brain's reward system

Go!

Substance abuse has been found to affect the brain
The main organ in the central nervous system
In two key ways
The first is that chronic substance abuse
Disrupts the brain's reward system

Substance abuse has been found
Chro-chro-chronic
Is that chronic substance abuse
Disrupts in two key ways
Chro-chro-chronic
Is that chronic substance-

Substance abuse has been found to affect the brain
The main organ in the central nervous system
In two key ways
The first is that chronic substance abuse
Disrupts the brain's reward system

Go!

Go-go-go!

Different drugs act in different ways
But the common outcome is
That dopamine builds up in the synapse
To a much greater amount than normal
This causes a continuous stimulation
Maybe overstimulation of receiving neurons

And is responsible for prolonged intense euphoria
Experienced by drug users
Repeated exposure to dopamine surges caused by drugs
Eventually de-sensitizes the reward system
The system is no longer responsive to everyday stimuli
The only thing that is rewarding is the drug
That is how drugs change the person's life